Publicaciones

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2012

  • Nock A, Ascano JM, Barrero MJ, Malik S. (2012) Mediator-regulated transcription through the +1 nucleosome. Mol Cell 48(6):837-48. Epub 2012 Nov 15.
  • Berniakovich I, Laricchia-Robbio L, Izpisua Belmonte JC. (2012) N-acetylcysteine protects induced pluripotent stem cells from in vitro stress: impact on differentiation outcome. Int J Dev Biol 56(9): 729-35.
  • Mateo S, Parriego M, Boada M, Vidal F, Coroleu B, Veiga A. (2012) In vitro development and chromosome constitution of embryos derived from monopronucleated zygotes after intracytoplasmic sperm injection. Fertil Steril Dec 13. [Epub ahead of print].
  • Izpisúa Belmonte JC. (2012) Reprogramming development and aging: cell differentiation as a malleable process. Curr Opin Cell Biol 24(6): 713-5. [Epub ahead of print].
  • Mo Li, Juan Carlos Izpisua Belmonte. (2012) No factor left behind: generation of transgene-free induced pluripotent stem cells. Am J Stem Cells 1(1):75-80.
  • Okamura D, Maeda I, Taniguchi H, Tokitake Y, Ikeda M, Ozato K, Mise N, Abe K, Noce T, Izpisua Belmonte JC, Matsui Y. (2012) Cell cycle gene- specific control of transcription has a critical role in proliferation of primordial germ cells. Genes Dev. 26(22): 2477-82.
  • Jopling C, Suñè G, Faucherre A, Fabregat C, Izpisua Belmonte JC. (2012) Hypoxia Induces Myocardial Regeneration in Zebrafish. Circulation 126(25):3017-27. Epub 2012 Nov 14.
  • Yang SL, Harnish E, Leeuw T, Dietz U, Batchelder E, Wright PS, Peppard J, August P, Volle-Challier C, Bono F, Herbert JM, Izpisúa Belmonte JC. (2012) Compound screening platform using human induced pluripotent stem cells to identify small molecules that promote chondrogenesisProtein Cell 3(12):934-42. Epub 2012 Nov 17.
  • Guang-Hui Liu, Jing Qu, Keiichiro Suzuki, Emmanuel Nivet, Mo Li, Nuria Montserrat, Fei Yi, Xiuling Xu, Sergio Ruiz, Weiqi Zhang, Ulrich Wagner, Audrey Kim, Bing Ren, Ying Li, April Goebl, Jessica Kim, Rupa Devi Soligalla, Ilir Dubova, James Thompson, John Yates III, Concepcion Rodriguez Esteban, Ignacio Sancho-Martinez & Juan Carlos Izpisúa Belmonte. (2012) Progressive degeneration of human neural stem cells caused by pathogenic LRRK2. Nature 491(7425):603-7. Epub 2012 Oct 17.
  • Masuda S, Izpisua Belmonte JC. (2012) Trametinib for patients with advanced melanoma. Lancet Oncology (10): e409
  • Ruiz S, Panopoulos AD, Montserrat N, Multon MC, Daury A, Rocher C, Spanakis E, Batchelder EM, Orsini C, Deleuze JF, Izpisua Belmonte JC. (2012) Generation of a drug-inducible reporter system to study cell reprogramming in human cells.
    J Biol Chem 287(48):40767-78. Epub 2012 Sep 27.
  • Liu GH, Ding Z, Izpisua Belmonte JC. (2012) iPSC technology to study human aging and aging-related disorders. Curr Opin Cell Biol 24(6):765-74. Epub 2012 Sep 18.
  • Ruiz, S, Diep, D, Goreb, A, Panopoulos, AD, Montserrat, N, Plongthongkumb, N, Kumara, S, Fung, HL, Giorgetti, A, Bilic, J, Batchelder, EM, Zaehres, H, Kan, NG, Schöler, HR, Mercola, M, Zhang, K, and Izpisua Belmonte JC. (2012)
    Identification of a specific reprogramming-associated epigenetic signature in human induced pluripotent stem cells. P Natl Acad Sci USA 109(40):16196-201. Epub 2012 Sep 18.
  • Murphy DA, Diaz B, Bromann PA, Tsai JH, Kawakami Y, Maurer J, Stewart RA, Izpisúa-Belmonte JC, Courtneidge SA. (2012) Correction: A Src-Tks5 Pathway Is Required for Neural Crest Cell Migration during Embryonic Development.
    PLoS One 7(8)
  • Sancho-Martinez I, Baek SH, Izpisua Belmonte JC. (2012) Lineage conversion methodologies meet the reprogramming toolbox.
    Nat Cell Biol 14(9): 892-9
  • Zhang K, Yi F, Liu GH, Izpisúa Belmonte, JC. (2012) Huntington's disease: Dancing in a dish.
    Cell Res 22 (12): 1627-30. Epub 2012 Aug 7.
  • Willems E, Cabral-Teixeira J, Schade D, Cai W, Reeves P, Bushway PJ, Lanier M, Walsh C, Kirchhausen T, Izpisua Belmonte JC, Cashman J, Mercola M. (2012) Small Molecule-Mediated TGF-β Type II Receptor Degradation Promotes Cardiomyogenesis in Embryonic Stem Cells.
    Cell Stem Cell 11(2):242-52
  • Li M, Liu GH and Izpisúa Belmonte JC. (2012) Navigating the epigenetic landscape of pluripotent stem cells.
    Nat Rev Mol Cell Biol
    13(8): 524-35
  • Giorgetti A, Marchetto MC, Li M, Yu D, Fazzina R, Mu Y, Adamo A, Paramonov I, Cardoso JC, Monasterio MB, Bardy C, Cassiani-Ingoni R, Liu GH, Gage FH and Izpisúa Belmonte JC. (2012) Cord blood-derived neuronal cells by ectopic expression of Sox2 and c-Myc. P Natl Acad Sci USA 109(31):12556-61. Epub 2012 Jul 18.
  • Yi F, Qu J, Li M, Suzuki K, Kim NY, Liu GH and Izpisúa Belmonte JC. (2012) Establishment of hepatic and neural differentiation platforms of Wilson's disease specific induced pluripotent stem cells.
    Protein Cell J3(119: 855-63. Epub 2012 JUl. 18.
  • Masuda S, Monserrat N, Okamura D, Suzuki K and Izpisúa Belmonte JC. (2012) Cardiosphere-derived cells for heart regeneration.
    Lancet 379(9835): 2425-6.
  • Arán B, Solé M, Rodriguez-Pizà I, Parriego M, Muñoz Y, Boada M, Barri PN, Izpisúa Belmonte JC and Veiga A. (2012) Vitrified blastocysts from Preimplantation Genetic Diagnosis (PGD) as a source for human Embryonic Stem Cell (hESC) derivation.
    J Assist Reprod Genet  29(10): 1013-20. Epub 2012 Juny 27.
  • Cai N, Li M, Qu J, Liu GH and Izpisúa Belmonte JC. Post-translational modulation of pluripotency. J Mol Cell Biol 4(4):262-5. Epub 2012 Jun 7.
  • Christen B, Cavaco Rodrigues AM, Barragán Monasterio M, Fabregat Roig C and Izpisúa Belmonte JC. Transient downregulation of Bmp signalling induces extra limbs in vertebrates.
    Development 139(14): 2557-65.
  • Barrero MJ, Berdasco M, Paramonov I, Bilic J, Vitaloni M, Esteller M and Izpisúa Belmonte JC. DNA Hypermethylation in Somatic Cells Correlates with Higher Reprogramming Efficiency.
    Stem Cells
    30(8): 1696-702.
  • Gu Y, Liu GH and Izpisúa Belmonte JC. (2012) Gametogenesis in a dish.
    Cell Res 22(10):1422-5. Epub 2012 May 29.
  • Letamendia A, Quevedo C, Ibarbia I, Virto JM, Holgado O, Diez M, Izpisúa Belmonte JC and Callol-Massot C. Development and validation of an automated high-throughput system for zebrafish in vivo screenings.
    PLoS One
    7(5): e36690.
  • Montserrat N, Ramirez-Bajo MJ, Xia Y, Sancho-Martinez I, Moya-Rull D, Miquel-Serra L, Yang S, Nivet E, Cortina C, Gonzalez F, Izpisúa Belmonte JC and Campistol JM. (2012) Generation of induced pluripotent stem cells from human renal proximal tubular cells with only two transcription factors: OCT4 and SOX2.
    J Biol Chem
    287(29):24131-8. Epub 2012 May 21.
  • Panopoulos AD and Izpisúa Belmonte JC. Induced pluripotent stem cells in clinical hematology: potentials, progress, and remaining obstacles.
    Curr Opin Hematol 
    19(4): 256-60.
  • Liu GH, Yi F, Suzuki K, Qu J and Izpisúa Belmonte JC. Induced neural stem cells: a new tool for studying neural development and neurological disorders.
    Cell Res
    22(7): 1087-91.
  • Vassena R, Montserrat N, Canal BC, Aran B, de Oñate L, Veiga A and Izpisúa Belmonte JC. Accumulation of instability in serial differentiation and reprogramming of parthenogenetic human cells.
    Hum Mol Genet
    21(15): 3366-73.
  • Xu X, Qu J, Suzuki K, Li M, Zhang W, Liu GH and Izpisúa Belmonte JC.  Reprogramming based gene therapy for inherited red blood cell disorders.
    Cell Res
    22(6): 941-4. 
  • Yi F, Liu GH and Izpisúa Belmonte JC. Human induced pluripotent stem cells derived hepatocytes: rising promise for disease modeling, drug development and cell therapy.
    Protein Cell
    3(4): 246-50.
  • Jopling C, Suñé G, Morera C and Izpisúa Belmote JC. p38α MAPK regulates myocardial regeneration in zebrafish.
    Cell Cycle
    11(6): 1195-201.
  • Liu GH, Li M, Qu J and Izpisúa Belmonte JC. Gating neural development and aging via nuclear pores.
    Cell Res
    22:1212-1214. Epub 2012 Mar 13.
  • Yi F, Liu GH and Izpisúa Belmonte JC. Rejuvenating liver and pancreas through cell transdifferentiation.
    Cell Res
    22(4): 616-9.
  • Cavaco Rodrigues AM, Christen B, Marti M and Izpisúa Belmonte JC.  Skeletal muscle regeneration in Xenopus tadpoles and zebrafish larvae.
    BMC Dev Biol 12(1): 9.
  • Montserrat N, Aran B and Izpisúa Belmonte JC. Cellules Mare Embrionàries: Què en Sabem Després de Trenta Anys D'Investigacio?
    Treballs de la SCB 63: 215-233.
  • Bilic J and Izpisúa Belmonte JC. Concise review: induced pluripotent stem cells versus embryonic stem cells: close enough or yet too far apart?
    Stem Cells 30(1): 33-41.
  • Liu G-H, Sancho-Martinez I and Izpisúa Belmonte JC. Cut and Paste: restoring cellular function by gene correction.
    Cell Research 22(2): 283-4.
  • Menendez S, Camus S, Herreria A, Paramonov I, Batlle Morera L, Collado M, Pekarik V, Maceda I, Edel M, Consiglio A, Sanchez A, Li H, Serrano M and Izpisúa Belmonte JC. Increased dosage of tumor suppressors limits the tumorigenicity of iPS cells without affecting their pluripotency.
    Aging Cell
    11(1): 41-50.
  • Panopoulos AD, Yanes O, Ruiz S, Kida YS, Diep D, Tautenhahn R, Herrerías A, Batchelder EM, Plongthongkum N, Lutz M, Berggren WT, Zhang K, Evans RM, Siuzdak G and Izpisúa Belmonte JC. The metabolome of induced pluripotent stem cells reveals metabolic changes occurring in somatic cell reprogramming.
    Cell Res
    22(1): 168-77.
  • Sanchez-Danes A, Consiglio A, Richaud Y, Rodriguez-Piza I, Dehay B, Edel M, Bove J, Memo M, Vila M, Raya A and Izpisua Belmonte JC.  Efficient generation of A9 midbrain dopaminergic neurons by lentiviral delivery of

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